TNFRSF14 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TNFRSF14 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MEPPGDWGPPPWRSTPKTDVLRLVLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTVGLIICVKRRKPRGDVVKVIVSVQRKRQEAEGEATVIEALQAPPDVTTVAVEETIPSFTGRSPNH
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — TNFRSF14
Entrez GeneID
8764GeneBank Accession#
NM_003820.2Protein Accession#
NP_003811.2Gene Name
TNFRSF14
Gene Alias
ATAR, HVEA, HVEM, LIGHTR, TR2
Gene Description
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Omim ID
602746Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq
Other Designations
CD40-like protein|OTTHUMP00000000866|herpesvirus entry mediator A|tumor necrosis factor receptor superfamily, member 14|tumor necrosis factor receptor-like gene2
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Interactome
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Pathway
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Disease
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