TNFRSF14 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF14 full-length
Host
Human
Theoretical MW (kDa)
31.24
Interspecies Antigen Sequence
Mouse (45); Rat (42)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF14 antibody (H00008764-B01) by Western Blots.
Western Blot
Lane 1: TNFRSF14 transfected lysate ( 30.4 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
TNFRSF14 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFRSF14
Entrez GeneID
8764GeneBank Accession#
NM_003820Protein Accession#
NP_003811Gene Name
TNFRSF14
Gene Alias
ATAR, HVEA, HVEM, LIGHTR, TR2
Gene Description
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Omim ID
602746Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq
Other Designations
CD40-like protein|OTTHUMP00000000866|herpesvirus entry mediator A|tumor necrosis factor receptor superfamily, member 14|tumor necrosis factor receptor-like gene2
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