TNFRSF14 monoclonal antibody (M13), clone 5B1
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More Files
- More Functions
Western Blot detection against Immunogen (20.13 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFRSF14.
Immunogen
TNFRSF14 (AAH02794.1, 38 a.a. ~ 200 a.a) partial recombinant protein.
Sequence
ALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKCSWLVTKAGAGTSSSH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (45); Rat (42)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (20.13 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TNFRSF14
Entrez GeneID
8764GeneBank Accession#
BC002794.1Protein Accession#
AAH02794.1Gene Name
TNFRSF14
Gene Alias
ATAR, HVEA, HVEM, LIGHTR, TR2
Gene Description
tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
Omim ID
602746Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq
Other Designations
CD40-like protein|OTTHUMP00000000866|herpesvirus entry mediator A|tumor necrosis factor receptor superfamily, member 14|tumor necrosis factor receptor-like gene2
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Interactome
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Pathway
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Disease
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