PABPC4 293T Cell Transient Overexpression Lysate(Denatured)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
SDS-PAGE Gel
PABPC4 transfected lysate.
Western Blot
Lane 1: PABPC4 transfected lysate ( 72.71 KDa)
Lane 2: Non-transfected lysate.
-
Specification
Transfected Cell Line
293T
Plasmid
pCMV-PABPC4 full-length
Host
Human
Theoretical MW (kDa)
72.71
Interspecies Antigen Sequence
Mouse (97); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PABPC4 antibody (H00008761-B01) by Western Blots.
SDS-PAGE Gel
PABPC4 transfected lysate.
Western Blot
Lane 1: PABPC4 transfected lysate ( 72.71 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot
-
Gene Info — PABPC4
Entrez GeneID
8761GeneBank Accession#
BC071591.1Protein Accession#
AAH71591.1Gene Name
PABPC4
Gene Alias
APP-1, APP1, FLJ43938, PABP4, iPABP
Gene Description
poly(A) binding protein, cytoplasmic 4 (inducible form)
Omim ID
603407Gene Ontology
HyperlinkGene Summary
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000010668|inducible poly(A)-binding protein|poly A binding protein, cytoplasmic 4
-
Interactome
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com