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CDS2 rabbit monoclonal antibody

  • Catalog # : H00008760-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CDS2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CDS2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CDS2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8760
  • GeneBank Accession#:
  • CDS2
  • Gene Name:
  • CDS2
  • Gene Alias:
  • FLJ38111
  • Gene Description:
  • CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
  • Gene Summary:
  • Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq
  • Other Designations:
  • CDP-DAG synthase 2,CDP-DG synthetase 2,CDP-diacylglycerol synthase 2,CDP-diglyceride diphosphorylase 2,CDP-diglyceride pyrophosphorylase 2,CDP-diglyceride synthetase 2,CTP:phosphatidate cytidylyltransferase 2,OTTHUMP00000030195,phosphatidate cytidylyltran
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