TNFSF13 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TNFSF13 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TNFSF13 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TNFSF13 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TNFSF13
Entrez GeneID
8741GeneBank Accession#
TNFSF13Gene Name
TNFSF13
Gene Alias
APRIL, CD256, TALL2, TRDL-1, UNQ383/PRO715, ligand
Gene Description
tumor necrosis factor (ligand) superfamily, member 13
Omim ID
604472Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Other transcripts that skip the last exon of the upstream gene (TNFSF12) and continue with the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq
Other Designations
OTTHUMP00000174780|TNF- and APOL-related leukocyte expressed ligand 2|a proliferation inducing ligand|tumor necrosis factor (ligand) superfamily member 13 transcript variant delta|tumor necrosis factor ligand superfamily member 13 epsilon|tumor necrosis f
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