TNFSF14 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66); Rat (68)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TNFSF14 transfected lysate using mouse monoclonal anti-TNFSF14 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TNFSF14.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-TNFSF14 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-TNFSF14 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TNFSF14
Entrez GeneID
8740Gene Name
TNFSF14
Gene Alias
CD258, HVEML, LIGHT, LTg, TR2
Gene Description
tumor necrosis factor (ligand) superfamily, member 14
Omim ID
604520Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
delta transmembrane LIGHT|herpesvirus entry mediator A|ligand for herpesvirus entry mediator|tumor necrosis factor ligand superfamily, member 14|tumor necrosis factor receptor-like 2|tumor necrosis factor superfamily member LIGHT
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