C19orf2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
C19orf2 transfected lysate.
Western Blot
Lane 1: C19orf2 transfected lysate ( 54.56 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-C19orf2 full-length
Host
Human
Theoretical MW (kDa)
54.56
Interspecies Antigen Sequence
Mouse (75); Rat (74)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-C19orf2 antibody (H00008725-B01) by Western Blots.
SDS-PAGE Gel
C19orf2 transfected lysate.
Western Blot
Lane 1: C19orf2 transfected lysate ( 54.56 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — C19orf2
Entrez GeneID
8725GeneBank Accession#
NM_134447.1Protein Accession#
NP_604431.1Gene Name
C19orf2
Gene Alias
FLJ10575, NNX3, RMP, URI
Gene Description
chromosome 19 open reading frame 2
Omim ID
603494Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
RNA polymerase II, subunit 5-mediating protein|RPB5-mediating protein|unconventional prefoldin RPB5 interactor
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Interactome
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Disease
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