C19orf2 (Human) Recombinant Protein (Q01)

Catalog # H00008725-Q01

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Size:25 ug
Price: USD $ 510.00
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Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human C19orf2 partial ORF ( NP_003787, 371 a.a. - 475 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    NSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPE

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    37.29

    Interspecies Antigen Sequence

    Mouse (75); Rat (74)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — C19orf2

    Entrez GeneID

    8725

    GeneBank Accession#

    NM_003796

    Protein Accession#

    NP_003787

    Gene Name

    C19orf2

    Gene Alias

    FLJ10575, NNX3, RMP, URI

    Gene Description

    chromosome 19 open reading frame 2

    Omim ID

    603494

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq

    Other Designations

    RNA polymerase II, subunit 5-mediating protein|RPB5-mediating protein|unconventional prefoldin RPB5 interactor

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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