TRADD (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of TRADD transfected lysate using mouse monoclonal anti-TRADD and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TRADD.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (76)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TRADD transfected lysate using mouse monoclonal anti-TRADD and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TRADD.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-TRADD (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-TRADD (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TRADD
Entrez GeneID
8717Gene Name
TRADD
Gene Alias
Hs.89862, MGC11078
Gene Description
TNFRSF1A-associated via death domain
Omim ID
603500Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq
Other Designations
TNFR1-associated death domain protein|tumor necrosis factor receptor type 1 associated death domain protein|tumor necrosis factor receptor-1-associated protein
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Interactome
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Pathway
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Disease
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