Products

Western Blot (Transfected lysate)

Western Blot analysis of B3GALT4 expression in transfected 293T cell line (H00008705-T01) by B3GALT4 MaxPab polyclonal antibody.

Lane 1: B3GALT4 transfected lysate(41.58 KDa).
Lane 2: Non-transfected lysate.

Entrez GeneID

8705

GeneBank Accession#

NM_003782

Protein Accession#

NP_003773

Gene Name

B3GALT4

Gene Alias

DJ1033B10.3, Gal-T2, GalT4, beta3GALT4, beta3Gal-T4

Gene Description

UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4

Omim ID

603095

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq

Other Designations

OTTHUMP00000029128|UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 4|beta-3-galactosyltransferase 4