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Last updated: 2016/11/27

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B4GALT3 rabbit monoclonal antibody

  • Catalog # : H00008703-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human B4GALT3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human B4GALT3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human B4GALT3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8703
  • Gene Name:
  • B4GALT3
  • Gene Alias:
  • beta4Gal-T3
  • Gene Description:
  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
  • Gene Summary:
  • This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032247,OTTHUMP00000032248,UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 3,UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3,beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3
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