ALDH4A1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ALDH4A1 protein.
Immunogen
ALDH4A1 (NP_003739.2, 1 a.a. ~ 563 a.a) full-length human protein.
Sequence
MLLPAPALRRALLSRPWTGAGLRWKHTSSLKVANEPVLAFTQGSPERDALQKALKDLKGRMEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKSLLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPRRAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAVELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGGNLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPPNIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLWKQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVSGTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHSRIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPSLTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGPVLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVVQEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTNDKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (92); Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ALDH4A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH4A1 expression in mouse kidney.Western Blot (Tissue lysate)
ALDH4A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH4A1 expression in human liver.Western Blot (Cell lysate)
ALDH4A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH4A1 expression in NIH/3T3.Western Blot (Cell lysate)
ALDH4A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH4A1 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of ALDH4A1 expression in transfected 293T cell line (H00008659-T02) by ALDH4A1 MaxPab polyclonal antibody.
Lane 1: ALDH4A1 transfected lysate(61.70 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ALDH4A1
Entrez GeneID
8659GeneBank Accession#
NM_003748.2Protein Accession#
NP_003739.2Gene Name
ALDH4A1
Gene Alias
ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS
Gene Description
aldehyde dehydrogenase 4 family, member A1
Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000002544|OTTHUMP00000002545|P5C dehydrogenase|aldehyde dehydrogenase 4A1|mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase
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Interactome
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Pathway
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Disease
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