Products

Western Blot

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

DDX3Y

Gene Alias

DBY

Gene Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked

Omim ID

Gene Ontology

Gene Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. The gene mutation causes male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that this gene plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq

Other Designations

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome|OTTHUMP00000034504