NUMB polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (40.96 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant NUMB.
Immunogen
NUMB (AAH33824, 1 a.a. ~ 135 a.a) full-length recombinant protein with GST tag.
Sequence
MPYPAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (84)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.96 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NUMB
Entrez GeneID
8650GeneBank Accession#
BC033824Protein Accession#
AAH33824Gene Name
NUMB
Gene Alias
S171
Gene Description
numb homolog (Drosophila)
Omim ID
603728Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
numb homolog
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Interactome
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Pathway
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Disease
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