MAPKSP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MAPKSP1 full-length ORF ( NP_068805.1, 1 a.a. - 124 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MADDLKRFLYKKLPSVEGLHAIVVSDRDGVPVIKVANDNAPEHALRPGFLSTFALATDQGSKLGLSKNKSIICYYNTYQVVQFNRLPLVVSFIASSSANTGLIVSLEKELAPLFEELRQVVEVS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
40
Interspecies Antigen Sequence
Mouse (98); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MAPKSP1
Entrez GeneID
8649GeneBank Accession#
NM_021970.2Protein Accession#
NP_068805.1Gene Name
MAPKSP1
Gene Alias
MAP2K1IP1, MAPBP, MP1
Gene Description
MAPK scaffold protein 1
Omim ID
603296Gene Ontology
HyperlinkGene Summary
This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Multiple transcript variants are expressed by this gene, but only one variant is thought to express a protein. [provided by RefSeq
Other Designations
MEK binding partner 1|MEK partner 1|mitogen-activated protein kinase kinase 1 interacting protein 1
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Interactome
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Pathway
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