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ABCB11 Pre-design Chimera RNAi

  • Catalog # : H00008647-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ABCB11), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003742
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8647
  • Gene Name:
  • ABCB11
  • Gene Alias:
  • ABC16,BSEP,PFIC-2,PFIC2,PGY4,SPGP
  • Gene Description:
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq
  • Other Designations:
  • ABC member 16, MDR/TAP subfamily,bile salt export pump,progressive familial intrahepatic cholestasis 2,sister p-glycoprotein
  • Gene Pathway
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