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AKR1C3 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008644-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-AKR1C3 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 35.53
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-AKR1C3 antibody (H00008644-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008644-T01
    AKR1C3 transfected lysate
    Western Blot
    QC Testing of H00008644-T01
    Lane 1: AKR1C3 transfected lysate ( 35.53 KDa).
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8644
  • Gene Name:
  • AKR1C3
  • Gene Alias:
  • Gene Description:
  • aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
  • Gene Summary:
  • This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018996,aldo-keto reductase family 1, member C3,chlordecone reductase,dihydrodiol dehydrogenase 3,dihydrodiol dehydrogenase X,hydroxysteroid (17-beta) dehydrogenase 5,prostaglandin F synthase,trans-1,2-dihydrobenzene-1,2-diol dehydrogenase,type
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