AOC3 monoclonal antibody (M06), clone 4B8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant AOC3.
Immunogen
AOC3 (NP_003725, 351 a.a. ~ 450 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DVRFQGERLVYEISLQEALAIYGGNSPAAMTTRYVDGGFGMGKYTTPLTRGVDCPYLATYVDWHFLLESQAPKTIRDAFCVFEQNQGLPLRRHHSDLYSH
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged AOC3 is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to AOC3 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — AOC3
Entrez GeneID
8639GeneBank Accession#
NM_003734Protein Accession#
NP_003725Gene Name
AOC3
Gene Alias
HPAO, SSAO, VAP-1, VAP1
Gene Description
amine oxidase, copper containing 3 (vascular adhesion protein 1)
Omim ID
603735Gene Ontology
HyperlinkGene Summary
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream. [provided by RefSeq
Other Designations
amine oxidase, copper containing 3|copper amine oxidase|semicarbazide-sensitive amine oxidase|vascular adhesion protein 1
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Interactome
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Pathway
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Publication Reference
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Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model.
Danoy M, Shinohara M, Rizki-Safitri A, Collard D, Senez V, Sakai Y.
Integrative Biology : Quantitative Biosciences from Nano to Macro 2017 Apr; 9(4):350.
Application:IF, Human, Rat, HUVEC, LX-2 cells, Rat hepatocytes.
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Alteration of pancreatic carcinoma and promyeloblastic cell adhesion in liver microvasculature by co-culture of hepatocytes, hepatic stellate cells and endothelial cells in a physiologically-relevant model.
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