UNC5C (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human UNC5C partial ORF ( AAH41156, 498 a.a. - 597 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
IKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.41
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UNC5C
Entrez GeneID
8633GeneBank Accession#
BC041156Protein Accession#
AAH41156Gene Name
UNC5C
Gene Alias
UNC5H3
Gene Description
unc-5 homolog C (C. elegans)
Omim ID
603610Gene Ontology
HyperlinkGene Summary
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq
Other Designations
homolog of C. elegans transmembrane receptor Unc5|unc5 (C.elegans homolog) c|unc5C
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Interactome
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