UNC5C monoclonal antibody (M01), clone 3C9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant UNC5C.
Immunogen
UNC5C (AAH41156, 498 a.a. ~ 597 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IKVYNTSGAVTPQDDLSEFTSKLSPQMTQSLLENEALSLKNQSLARQTDPSCTAFGSFNSLGGHLIVPNSGVSLLIPAGAIPQGRVYEMYVTVHRKETMR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — UNC5C
Entrez GeneID
8633GeneBank Accession#
BC041156Protein Accession#
AAH41156Gene Name
UNC5C
Gene Alias
UNC5H3
Gene Description
unc-5 homolog C (C. elegans)
Omim ID
603610Gene Ontology
HyperlinkGene Summary
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq
Other Designations
homolog of C. elegans transmembrane receptor Unc5|unc5 (C.elegans homolog) c|unc5C
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Interactome
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