SCAP1 monoclonal antibody (M02), clone 1C11
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SCAP1.
Immunogen
SCAP1 (NP_003717, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDYQDEGMEDIVK
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SCAP1 monoclonal antibody (M02), clone 1C11 Western Blot analysis of SCAP1 expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SCAP1 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — SKAP1
Entrez GeneID
8631GeneBank Accession#
NM_003726Protein Accession#
NP_003717Gene Name
SKAP1
Gene Alias
SCAP1, SKAP55
Gene Description
src kinase associated phosphoprotein 1
Omim ID
604969Gene Ontology
HyperlinkGene Summary
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq
Other Designations
src family associated phosphoprotein 1|src kinase-associated phosphoprotein of 55 kDa
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Interactome
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Disease
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