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RFXANK 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008625-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-RFXANK full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 25.6
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-RFXANK antibody (H00008625-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00008625-T01
    RFXANK transfected lysate.
    Western Blot
    QC Testing of H00008625-T01
    Lane 1: RFXANK transfected lysate ( 25.6 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8625
  • Gene Name:
  • RFXANK
  • Gene Alias:
  • ANKRA1,BLS,F14150_1,MGC138628,RFX-B
  • Gene Description:
  • regulatory factor X-associated ankyrin-containing protein
  • Gene Summary:
  • Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq
  • Other Designations:
  • DNA-binding protein RFXANK,RFX-Bdelta4,ankyrin repeat-containing regulatory factor X-associated protein,regulatory factor X subunit B
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