RFXANK (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human RFXANK.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (72)
Quality Control Testing
Standard curve using recombinant protein ( H00008625-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 3 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-RFXANK (100 ug)
2. Detection antibody: mouse purified polyclonal anti-RFXANK (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — RFXANK
Entrez GeneID
8625Gene Name
RFXANK
Gene Alias
ANKRA1, BLS, F14150_1, MGC138628, RFX-B
Gene Description
regulatory factor X-associated ankyrin-containing protein
Gene Ontology
HyperlinkGene Summary
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq
Other Designations
DNA-binding protein RFXANK|RFX-Bdelta4|ankyrin repeat-containing regulatory factor X-associated protein|regulatory factor X subunit B
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Interactome
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Pathway
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