DSCR2 monoclonal antibody (M01), clone 4F2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant DSCR2.
Immunogen
DSCR2 (AAH03619, 1 a.a. ~ 288 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAATFFGEVVKAPCRAGTEDEEEEEEGRRETPEDREVRLQLARKREVRLLRRQTKTSLEVSLLEKYPCSKFIIAIGNNAVAFLSSFVMNSGVWEEVGCAKLWNEWCRTTDTTHLSSTEAFCVFYHLKSNPSVFLCQCSCYVAEDQQYQWLEKVFGSCPRKNMQITILTCRHVTDYKTSESTGSLPSPFLRALKTQNFKDSACCPLLEQPNIVHDLPAAVLSYCQVWKIPAILYLCYTDVMKLDLITVEAFKPILSTRSLKGLVKNIPQSTEILKKLMTTNEIQSNIYT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DSCR2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — PSMG1
Entrez GeneID
8624GeneBank Accession#
BC003619Protein Accession#
AAH03619Gene Name
PSMG1
Gene Alias
C21LRP, DSCR2, LRPC21, PAC1
Gene Description
proteasome (prosome, macropain) assembly chaperone 1
Omim ID
605296Gene Ontology
HyperlinkGene Summary
O
Other Designations
Down syndrome critical region gene 2|Down syndrome critical region protein 2|chromosome 21 leucine-rich protein|leucine rich protein C21-LRP|proteasome assembling chaperone 1
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Interactome
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Disease
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Publication Reference
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Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver.
Dasuri K, Zhang L, Ebenezer P, Liu Y, Fernandez-Kim SO, Keller JN.
Mechanisms of Ageing and Development 2009 Nov; 130(11-12):777.
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Down syndrome critical region 2 protein inhibits the transcriptional activity of peroxisome proliferator-activated receptor beta in HEK293 cells.
Song HJ, Park J, Seo SR, Kim J, Paik SR, Chung KC.
Biochemical and Biophysical Research Communications 2008 Sep; 376(3):478.
Application:WB-Tr, Human, HEK 293 cells.
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Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver.
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