STC2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
Western Blot
Lane 1: STC2 transfected lysate ( 33.2 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
STC2 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-STC2 full-length
Host
Human
Theoretical MW (kDa)
33.33
Interspecies Antigen Sequence
Mouse (86); Rat (84)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-STC2 antibody (H00008614-B01) by Western Blots.
Western Blot
Lane 1: STC2 transfected lysate ( 33.2 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
STC2 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — STC2
Entrez GeneID
8614GeneBank Accession#
NM_003714Protein Accession#
NP_003705Gene Name
STC2
Gene Alias
STC-2, STCRP
Gene Description
stanniocalcin 2
Omim ID
603665Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq
Other Designations
STC-related protein|stanniocalcin-related protein
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Interactome
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Disease
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