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Last updated: 2016/10/23

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MADD Pre-design Chimera RNAi

  • Catalog # : H00008567-R12
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens MAP-kinase activating death domain (MADD), transcript variant 6, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_130474
  • Target Region:
  • Coding sequence
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.
    The related RNAi products listed below were designed from different accesion number but sharing the same RNAi sequence.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8567
  • Gene Name:
  • MADD
  • Gene Alias:
  • DENN,FLJ35600,FLJ36300,IG20,KIAA0358,RAB3GEP
  • Gene Description:
  • MAP-kinase activating death domain
  • Gene Summary:
  • Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • MAP-kinase activating death domain-containing protein,Rab3 GDP/GTP exchange factor,differentially expressed in normal and neoplastic cells,insulinoma-glucagonoma protein 20
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