TCAP (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human TCAP full-length ORF ( AAH13330, 1 a.a. - 167 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGIHGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
44.11
Interspecies Antigen Sequence
Mouse (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TCAP
Entrez GeneID
8557GeneBank Accession#
BC013330Protein Accession#
AAH13330Gene Name
TCAP
Gene Alias
CMD1N, LGMD2G, T-cap, TELE, telethonin
Gene Description
titin-cap (telethonin)
Gene Ontology
HyperlinkGene Summary
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq
Other Designations
19 kDa sarcomeric protein|limb girdle muscular dystrophy 2G (autosomal recessive)|telethonin
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Interactome
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Disease
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