TCAP monoclonal antibody (M01), clone 2B1
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TCAP is approximately 0.1ng/ml as a capture antibody.
Western Blot detection against Immunogen (44.11 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant TCAP.
Immunogen
TCAP (AAH12628, 1 a.a. ~ 167 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90)
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (44.11 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TCAP is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — TCAP
Entrez GeneID
8557GeneBank Accession#
BC012628Protein Accession#
AAH12628Gene Name
TCAP
Gene Alias
CMD1N, LGMD2G, T-cap, TELE, telethonin
Gene Description
titin-cap (telethonin)
Gene Ontology
HyperlinkGene Summary
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq
Other Designations
19 kDa sarcomeric protein|limb girdle muscular dystrophy 2G (autosomal recessive)|telethonin
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Interactome
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Disease
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