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Last updated: 2016/10/23

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TCAP rabbit monoclonal antibody

  • Catalog # : H00008557-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human TCAP peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human TCAP is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human TCAP peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 8557
  • GeneBank Accession#:
  • TCAP
  • Gene Name:
  • TCAP
  • Gene Alias:
  • CMD1N,LGMD2G,T-cap,TELE,telethonin
  • Gene Description:
  • titin-cap (telethonin)
  • Gene Summary:
  • Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. [provided by RefSeq
  • Other Designations:
  • 19 kDa sarcomeric protein,limb girdle muscular dystrophy 2G (autosomal recessive),telethonin
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