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CDC14A rabbit monoclonal antibody

  • Catalog # : H00008556-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CDC14A peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CDC14A is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CDC14A peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 8556
  • Gene Name:
  • CDC14A
  • Gene Alias:
  • cdc14,hCDC14
  • Gene Description:
  • CDC14 cell division cycle 14 homolog A (S. cerevisiae)
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms. [provided by RefSeq
  • Other Designations:
  • CDC10 (cell division cycle 10, S. cerevisiae, homolog),CDC14 homolog A,OTTHUMP00000012653,OTTHUMP00000012654,OTTHUMP00000012655,dual specificity protein phosphatase CDC14A
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