CDC14B 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
CDC14B transfected lysate.
Western Blot
Lane 1: CDC14B transfected lysate ( 51.92 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-CDC14B full-length
Host
Human
Theoretical MW (kDa)
51.92
Interspecies Antigen Sequence
Mouse (85); Rat (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-CDC14B antibody (H00008555-B01) by Western Blots.
SDS-PAGE Gel
CDC14B transfected lysate.
Western Blot
Lane 1: CDC14B transfected lysate ( 51.92 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CDC14B
Entrez GeneID
8555GeneBank Accession#
ENST00000265659Protein Accession#
ENSP00000265659Gene Name
CDC14B
Gene Alias
CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Gene Description
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
Omim ID
603505Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
CDC14 homolog B|OTTHUMP00000021729|OTTHUMP00000021730|OTTHUMP00000063774
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Interactome
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Pathway
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