CDC14B (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CDC14B transfected lysate using rabbit polyclonal anti-CDC14B and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CDC14B.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CDC14B (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-CDC14B (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CDC14B
Entrez GeneID
8555Gene Name
CDC14B
Gene Alias
CDC14B3, Cdc14B1, Cdc14B2, hCDC14B
Gene Description
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
Omim ID
603505Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
CDC14 homolog B|OTTHUMP00000021729|OTTHUMP00000021730|OTTHUMP00000063774
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Interactome
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Pathway
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