FCN3 monoclonal antibody (M01A), clone 4B4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of FCN3 expression in transfected 293T cell line by FCN3 monoclonal antibody (M01A), clone 4B4.
Lane 1: FCN3 transfected lysate(31.7 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of FCN3 transfected lysate using anti-FCN3 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with FCN3 MaxPab rabbit polyclonal antibody.
Western Blot detection against Immunogen (57.42 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant FCN3.
Immunogen
FCN3 (AAH20731, 1 a.a. ~ 288 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPLTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR
Host
Mouse
Reactivity
Human
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (57.42 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of FCN3 expression in transfected 293T cell line by FCN3 monoclonal antibody (M01A), clone 4B4.
Lane 1: FCN3 transfected lysate(31.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of FCN3 transfected lysate using anti-FCN3 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with FCN3 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — FCN3
Entrez GeneID
8547GeneBank Accession#
BC020731Protein Accession#
AAH20731Gene Name
FCN3
Gene Alias
FCNH, HAKA1, MGC22543
Gene Description
ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)
Omim ID
604973Gene Ontology
HyperlinkGene Summary
Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified. [provided by RefSeq
Other Designations
H-ficolin|Hakata antigen|OTTHUMP00000006338|OTTHUMP00000006339|collagen/fibrinogen domain-containing lectin 3 p35|collagen/fibrinogen domain-containing protein 3|ficolin 3|ficolin-3
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Interactome
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Disease
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