PIR purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PIR protein.
Immunogen
PIR (NP_003653.1, 1 a.a. ~ 290 a.a) full-length human protein.
Sequence
MGSSKKVTLSVLSREQSEGVGARVRRSIGRPELKNLDPFLLFDEFKGGRPGGFPDHPHRGFETVSYLLEGGSMAHEDFCGHTGKMNPGDLQWMTAGRGILHAEMPCSEEPAHGLQLWVNLRSSEKMVEPQYQELKSEEIPKPSKDGVTVAVISGEALGIKSKVYTRTPTLYLDFKLDPGAKHSQPIPKGWTSFIYTISGDVYIGPDDAQQKIEPHHTAVLGEGDSVQVENKDPKRSHFVLIAGEPLREPVIQHGPFVMNTNEEISQAILDFRNAKNGFERAKTWKSKIGN
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PIR MaxPab rabbit polyclonal antibody. Western Blot analysis of PIR expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of PIR expression in transfected 293T cell line (H00008544-T01) by PIR MaxPab polyclonal antibody.
Lane 1: PIR transfected lysate(32.10 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PIR
Entrez GeneID
8544GeneBank Accession#
NM_003662.2Protein Accession#
NP_003653.1Gene Name
PIR
Gene Alias
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Gene Description
pirin (iron-binding nuclear protein)
Omim ID
603329Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
OTTHUMP00000022961|OTTHUMP00000022962|pirin
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