IKBKAP (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human IKBKAP partial ORF ( NP_003631, 1242 a.a. - 1331 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
VLFLFEFDEQGRELQKAFEDTLQLMERSLPEIWTLTYQQNSATPVLGPNSTANSIMASYQQQKTSVPVLDAELFIPPKINRRTQWKLSLL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.64
Interspecies Antigen Sequence
Mouse (73); Rat (77)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IKBKAP
Entrez GeneID
8518GeneBank Accession#
NM_003640Protein Accession#
NP_003631Gene Name
IKBKAP
Gene Alias
DKFZp781H1425, DYS, ELP1, FD, FLJ12497, IKAP, IKI3, TOT1
Gene Description
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq
Other Designations
OTTHUMP00000021869|OTTHUMP00000063889
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Interactome
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