PARG purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
PARG MaxPab polyclonal antibody. Western Blot analysis of PARG expression in Hela S3 NE.
Western Blot (Transfected lysate)
Western Blot analysis of PARG expression in transfected 293T cell line (H00008505-T01) by PARG MaxPab polyclonal antibody.
Lane 1: PARG transfected lysate(107.36 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PARG on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PARG protein.
Immunogen
PARG (NP_003622.2, 1 a.a. ~ 976 a.a) full-length human protein.
Sequence
MNAGPGCEPCTKRPRWGAATTSPAASDARSFPSRQRRVLDPKDAHVQFRVPPSSPACVPGRAGQHRGSATSLVFKQKTITSWMDTKGIKTAESESLDSKENNNTRIESMMSSVQKDNFYQHNVEKLENVSQLSLDKSPTEKSTQYLNQHQTAAMCKWQNEGKHTEQLLESEPQTVTLVPEQFSNANIDRSPQNDDHSDTDSEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGEDCASCQQDEIDVVPESPLSDVGSEDVGTGPKNDNKLTRQESCLGNSPPFEKESEPESPMDVDNSKNSCQDSEADEETSPGFDEQEDGSSSQTANKPSRFQARDADIEFRKRYSTKGGEVRLHFQFEGGESRTGMNDLNAKLPGNISSLNVECRNSKQHGKKDSKITDHFMRLPKAEDRRKEQWETKHQRTERKIPKYVPPHLSPDKKWLGTPIEEMRRMPRCGIRLPLLRPSANHTVTIRVDLLRAGEVPKPFPTHYKDLWDNKHVKMPCSEQNLYPVEDENGERTAGSRWELIQTALLNKFTRPQNLKDAILKYNVAYSKKWDFTALIDFWDKVLEEAEAQHLYQSILPDMVKIALCLPNICTQPIPLLKQKMNHSITMSQEQIASLLANAFFCTFPRRNAKMKSEYSSYPDINFNRLFEGRSSRKPEKLKTLFCYFRRVTEKKPTGLVTFTRQSLEDFPEWERCEKPLTRLHVTYEGTIEENGQGMLQVDFANRFVGGGVTSAGLVQEEIRFLINPELIISRLFTEVLDHNECLIITGTEQYSEYTGYAETYRWSRSHEDGSERDDWQRRCTEIVAIDALHFRRYLDQFVPEKMRRELNKAYCGFLRPGVSSENLSAVATGNWGCGAFGGDARLKALIQILAAAAAERDVVYFTFGDSELMRDIYSMHIFLTERKLTVGDVYKLLLRYYNEECRNCSTPGPDIKLYPFIYHAVESCAETADHSGQRTGT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PARG MaxPab polyclonal antibody. Western Blot analysis of PARG expression in Hela S3 NE.Western Blot (Transfected lysate)
Western Blot analysis of PARG expression in transfected 293T cell line (H00008505-T01) by PARG MaxPab polyclonal antibody.
Lane 1: PARG transfected lysate(107.36 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PARG on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PARG
Entrez GeneID
8505GeneBank Accession#
NM_003631.2Protein Accession#
NP_003622.2Gene Name
PARG
Gene Alias
PARG99
Gene Description
poly (ADP-ribose) glycohydrolase
Omim ID
603501Gene Ontology
HyperlinkGene Summary
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. [provided by RefSeq
Other Designations
poly(ADP-ribose) glycohydrolase 60 kDa isoform
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Interactome
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Disease
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Publication Reference
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PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels.
Boudra MT, Bolin C, Chiker S, Fouquin A, Zaremba T, Vaslin L, Biard D, Cordelieres FP, Megnin-Chanet F, Favaudon V, Fernet M, Pennaneach V, Hall J.
Cellular and Molecular Life Sciences 2015 Apr; 72(8):1585.
Application：WB-Tr, Human, HeLa, U2OS cells.
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Characterization and role of poly(ADP-ribosyl)ation in the Mediterranean species Cistus incanus L. under different temperature conditions.
Arena C, Mistretta C, Di Natale E, Faraone Mennella MR, De Santo AV, De Maio A.
Plant Physiology and Biochemistry 2011 Apr; 49(4):435.
Application：WB, Plant, Nuclear fractions from Plants.
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PARP-2 depletion results in lower radiation cell survival but cell line-specific differences in poly(ADP-ribose) levels.
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