PEX3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PEX3 full-length
Host
Human
Theoretical MW (kDa)
41.14
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PEX3 antibody (H00008504-B01) by Western Blots.
SDS-PAGE Gel
PEX3 transfected lysate.
Western Blot
Lane 1: PEX3 transfected lysate ( 41.14 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PEX3
Entrez GeneID
8504GeneBank Accession#
NM_003630.1Protein Accession#
NP_003621.1Gene Name
PEX3
Gene Alias
DKFZp686N14184, FLJ13531, TRG18
Gene Description
peroxisomal biogenesis factor 3
Gene Ontology
HyperlinkGene Summary
The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq
Other Designations
OTTHUMP00000017334|OTTHUMP00000040175|peroxin-3|peroxisomal assembly protein PEX3|transformation-related protein 18
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