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MAP4K3 Pre-design Chimera RNAi

  • Catalog # : H00008491-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_003618
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 8491
  • Gene Name:
  • MAP4K3
  • Gene Alias:
  • GLK,MAPKKKK3,RAB8IPL1
  • Gene Description:
  • mitogen-activated protein kinase kinase kinase kinase 3
  • Gene Summary:
  • This gene encodes a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3). [provided by RefSeq
  • Other Designations:
  • germinal center kinase-like kinase,germinal center kinase-related protein kinase
  • Gene Pathway
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