CILP polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant CILP.
Immunogen
CILP (NP_003604, 129 a.a. ~ 226 a.a) partial recombinant protein with GST tag.
Sequence
NCSNYTVRFLCPPGSLRRDTERIWSPWSPWSKCSAACGQTGVQTRTRICLAEMVSLCSEASEEGQHCMGQDCTACDLTCPMGQVNADCDACMCQDFML
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (88)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.89 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CILP
Entrez GeneID
8483GeneBank Accession#
NM_003613Protein Accession#
NP_003604Gene Name
CILP
Gene Alias
CILP-1, HsT18872
Gene Description
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
Gene Ontology
HyperlinkGene Summary
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for 2 different proteins, namely CILP and a homolog of NTPPHase, however later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. One isoform of the protein, CILP-1, functions as an IGF-1 antagonist. [provided by RefSeq
Other Designations
cartilage intermediate layer protein|cartilage intermediate layer protein 1 C1|cartilage intermediate layer protein 1 C2
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Interactomes
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Diseases
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