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CDC42BPA rabbit monoclonal antibody

  • Catalog # : H00008476-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CDC42BPA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CDC42BPA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CDC42BPA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8476
  • Gene Name:
  • CDC42BPA
  • Gene Alias:
  • DKFZp686L1738,DKFZp686P1738,FLJ23347,KIAA0451,MRCK,MRCKA,PK428
  • Gene Description:
  • CDC42 binding protein kinase alpha (DMPK-like)
  • Gene Summary:
  • The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq
  • Other Designations:
  • CDC42 binidng protein kinase beta,CDC42-binding protein kinase alpha,CDC42-binding protein kinase alpha (DMPK-like),OTTHUMP00000035727,OTTHUMP00000035728,myotonic dystrophy kinase-related CDC42-binding protein kinase alpha,ser-thr protein kinase PK428,ser
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