IRS4 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human IRS4 partial ORF ( NP_003595, 850 a.a. - 950 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.85
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IRS4
Entrez GeneID
8471GeneBank Accession#
NM_003604Protein Accession#
NP_003595Gene Name
IRS4
Gene Alias
IRS-4, PY160
Gene Description
insulin receptor substrate 4
Omim ID
603510Gene Ontology
HyperlinkGene Summary
IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq
Other Designations
OTTHUMP00000023837
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Interactome
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