DOC2A polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (70.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant DOC2A.
Immunogen
DOC2A (AAH63436, 1 a.a. ~ 400 a.a) full-length recombinant protein with GST tag.
Sequence
MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLALAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (70.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DOC2A
Entrez GeneID
8448GeneBank Accession#
BC063436Protein Accession#
AAH63436Gene Name
DOC2A
Gene Alias
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Gene Description
double C2-like domains, alpha
Omim ID
604567Gene Ontology
HyperlinkGene Summary
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Doc2 is a ca(2+) sensor required for asynchronous neurotransmitter release.
Yao J, Gaffaney JD, Kwon SE, Chapman ER.
Cell 2011 Oct; 147(3):666.
Application：WB-Ce, WB-Tr, Human, Mouse, HEK 293T cells, Hippocampal neurons.
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Doc2 is a ca(2+) sensor required for asynchronous neurotransmitter release.
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