DOC2B purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
DOC2B MaxPab polyclonal antibody. Western Blot analysis of DOC2B expression in human colon.
Western Blot (Transfected lysate)
Western Blot analysis of DOC2B expression in transfected 293T cell line (H00008447-T02) by DOC2B MaxPab polyclonal antibody.
Lane 1: DOC2B transfected lysate(45.32 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DOC2B protein.
Immunogen
DOC2B (AAI53025.1, 1 a.a. ~ 412 a.a) full-length human protein.
Sequence
MTLRRRGEKATISIQEHMAIDVCPGPIRPIKQISDYFPRFPRGLPPDAGPRAAAPPDAPARPAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSELPGAVLSD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DOC2B MaxPab polyclonal antibody. Western Blot analysis of DOC2B expression in human colon.Western Blot (Transfected lysate)
Western Blot analysis of DOC2B expression in transfected 293T cell line (H00008447-T02) by DOC2B MaxPab polyclonal antibody.
Lane 1: DOC2B transfected lysate(45.32 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DOC2B
Entrez GeneID
8447GeneBank Accession#
BC153024Protein Accession#
AAI53025.1Gene Name
DOC2B
Gene Alias
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Gene Description
double C2-like domains, beta
Omim ID
604568Gene Ontology
HyperlinkGene Summary
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca(2+)-dependent intracellular vesicle trafficking in various types of cells. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Doc2 is a ca(2+) sensor required for asynchronous neurotransmitter release.
Yao J, Gaffaney JD, Kwon SE, Chapman ER.
Cell 2011 Oct; 147(3):666.
Application：WB-Ce, WB-Tr, Human, Mouse, HEK 293T cells, Hippocampal neurons.
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Doc2 is a ca(2+) sensor required for asynchronous neurotransmitter release.
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