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Last updated: 2017/12/10

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DUSP11 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00008446-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DUSP11 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 36.41
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DUSP11 antibody (H00008446-B01) by Western Blots.
    Western Blot
    QC Testing of H00008446-T01
    Lane 1: DUSP11 transfected lysate ( 36.41 KDa)
    Lane 2: Non-transfected lysate.
    SDS-PAGE Gel
    QC Testing of H00008446-T01
    DUSP11 transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 8446
  • Gene Name:
  • DUSP11
  • Gene Alias:
  • PIR1
  • Gene Description:
  • dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
  • Gene Summary:
  • The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq
  • Other Designations:
  • RNA/RNP complex-interacting phosphatase,dual specificity phosphatase 11,serine/threonine specific protein phosphatase
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