DYRK3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DYRK3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DYRK3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DYRK3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DYRK3
Entrez GeneID
8444GeneBank Accession#
DYRK3Gene Name
DYRK3
Gene Alias
DYRK5, RED, REDK, hYAK3-2
Gene Description
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
Omim ID
603497Gene Ontology
HyperlinkGene Summary
This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000034527|OTTHUMP00000034528|OTTHUMP00000034529|dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5|protein kinase Dyrk3|regulatory erythroid kinase
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Interactome
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