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Last updated: 2017/10/15

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DYRK3 rabbit monoclonal antibody

  • Catalog # : H00008444-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DYRK3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DYRK3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DYRK3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8444
  • GeneBank Accession#:
  • DYRK3
  • Gene Name:
  • DYRK3
  • Gene Alias:
  • DYRK5,RED,REDK,hYAK3-2
  • Gene Description:
  • dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
  • Gene Summary:
  • This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000034527,OTTHUMP00000034528,OTTHUMP00000034529,dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5,protein kinase Dyrk3,regulatory erythroid kinase
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