NCK2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NCK2 protein.
Immunogen
NCK2 (NP_001004720.1, 1 a.a. ~ 380 a.a) full-length human protein.
Sequence
MTEEVIVIAKWDYTAQQDQELDIKKNERLWLLDDSKTWWRVRNAANRTGYVPSNYVERKNSLKKGSLVKNLKDTLGLGKTRRKTSARDASPTPSTDAEYPANGSGADRIYDLNIPAFVKFAYVAEREDELSLVKGSRVTVMEKCSDGWWRGSYNGQIGWFPSNYVLEEVDEAAAESPSFLSLRKGASLSNGQGSRVLHVVQTLYPFSSVTEEELNFEKGETMEVIEKPENDPEWWKCKNARGQVGLVPKNYVVVLSDGPALHPAHAPQISYTGPSSSGRFAGREWYYGNVTRHQAECALNERGVEGDFLIRDSESSPSDFSVSLKASGKNKHFKVQLVDNVYCIGQRRFHTMDELVEHYKKAPIFTSEHGEKLYLVRALQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
NCK2 MaxPab polyclonal antibody. Western Blot analysis of NCK2 expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of NCK2 expression in transfected 293T cell line (H00008440-T01) by NCK2 MaxPab polyclonal antibody.
Lane 1: NCK2 transfected lysate(41.8 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NCK2
Entrez GeneID
8440GeneBank Accession#
NM_001004720Protein Accession#
NP_001004720.1Gene Name
NCK2
Gene Alias
GRB4, NCKbeta
Gene Description
NCK adaptor protein 2
Omim ID
604930Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
SH2/SH3 adaptor protein NCK-beta|noncatalytic region of tyrosine kinase, beta
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Interactome
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Pathway
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Disease
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