NSMAF (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human NSMAF partial ORF ( NP_003571, 818 a.a. - 917 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RHVLSTGTDGCLNVIDVQTGMLISSMTSDEPQRCFVWDGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQIIFWKLQY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (92); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NSMAF
Entrez GeneID
8439GeneBank Accession#
NM_003580Protein Accession#
NP_003571Gene Name
NSMAF
Gene Alias
FAN
Gene Description
neutral sphingomyelinase (N-SMase) activation associated factor
Omim ID
603043Gene Ontology
HyperlinkGene Summary
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants
Other Designations
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Interactome
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Disease
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