RASAL1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-RASAL1 full-length
Host
Human
Theoretical MW (kDa)
85.47
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-RASAL1 antibody (H00008437-B01) by Western Blots.
SDS-PAGE Gel
RASAL1 transfected lysate.
Western Blot
Lane 1: RASAL1 transfected lysate ( 85.47 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — RASAL1
Entrez GeneID
8437GeneBank Accession#
BC014420Protein Accession#
AAH14420Gene Name
RASAL1
Gene Alias
RASAL
Gene Description
RAS protein activator like 1 (GAP1 like)
Omim ID
604118Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. [provided by RefSeq
Other Designations
GAP1 like protein|RAS protein activator like 1|RAS-GTPase-activating protein-like
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