RECK (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RECK partial ORF ( NP_066934, 701 a.a. - 800 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KFGCSQYECVPRQLACDQVQDPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RECK
Entrez GeneID
8434GeneBank Accession#
NM_021111Protein Accession#
NP_066934Gene Name
RECK
Gene Alias
ST15, hRECK
Gene Description
reversion-inducing-cysteine-rich protein with kazal motifs
Omim ID
605227Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. [provided by RefSeq
Other Designations
OTTHUMP00000021369|RECK protein|membrane-anchored glycoprotein (metastasis and invasion)|suppression of tumorigenicity 15 (reversion-inducing-cysteine-rich protein with kazal motifs)|suppression of tumorigenicity 5 (reversion-inducing-cysteine-rich protei
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Interactome
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Disease
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